The effect of anti-IL-6 receptor antibody for the treatment of McH-lpr/lpr-RA1 mice that spontaneously developed ankylosing arthritis
Y. Mori, T. Izumiyama, K. Takeda, N. Mori, S. Mori, T. Kodama, E. Itoi
This study evaluates the effectiveness of an anti-IL-6 receptor antibody in reducing synovitis and bone destruction in McH-lpr/lpr-RA1 mice with ankylosing arthritis, showing partial success in inflammation but not in preventing ankylosis progression.
bioRxiv · Jul 4, 2018Pathology