Author

E. J. Chory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

E. A. Debenedictis· 2 shared K. M. Esvelt· 2 shared S. Golas· 2 shared A. M. Michalowska· 1 shared B. E. Gryder· 1 shared B. Tu· 1 shared B. Wang· 1 shared B. Z. Stanton· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioengineering

E. A. Debenedictis

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Low-cost camera-based estrous tracking enables transgenesis in Peromyscus leucopus, the primary reservoir for Lyme disease

J. Buchthal, E. J. Chory, Z. Hill, C. Dennison, B. Tu, R. P. Wierenga, C. Cevrim, S. Golas, S. R. Telford, K. L. McKinley, R. Jaenisch, S. Markoulaki, K. M. Esvelt

bioRxiv · Oct 20, 2023 · PreprintBioengineering

High-throughput Approaches to Uncover Synergistic Drug Combinations in Leukemia

E. J. Chory, M. Wang, M. Ceribelli, A. M. Michalowska, S. Golas, E. Beck, C. Klumpp-Thomas, L. Chen, C. McKnight, Z. Itkin, S. Divakaran, J. Bradner, J. Khan, B. E. Gryder, C. J. Thomas, B. Z. Stanton

This paper identifies synergistic drug combinations in AML using high-throughput methods and open-source tools, revealing synergies affecting histone H3 lysine-27 modification.

SLAS Discovery · Jun 1, 2023Peer-reviewedCancer Biology

Flexible open-source automation for robotic bioengineering

E. J. Chory, D. W. Gretton, E. A. Debenedictis, K. M. Esvelt

The paper introduces Pyhamilton, an open-source Python package that enhances robotic liquid handling for bacterial assays, population dynamics, and bioreactor optimization.

bioRxiv · Apr 14, 2020 · PreprintBioengineering

A high-throughput platform for feedback-controlled directed evolution.

E. A. DeBenedictis, E. J. Chory, D. Gretton, B. Wang, K. Esvelt

PRANCE enables feedback-controlled continuous directed evolution of biomolecules through automation, real-time monitoring, and miniaturization, improving efficiency and reducing reagent use.

bioRxiv · Apr 1, 2020 · PreprintBioengineering

Inhibition of a Selective SWI/SNF Function Synergizes with ATR Inhibitors in Cancer Cell Killing

E. J. Chory, J. G. Kirkland, C.-y. Chang, V. D'Andrea, S. Gourisankar, E. J. Dykhuizen, G. J. Crabtree

The paper identifies small molecules that inhibit a specific repressive function of SWI/SNF complexes, which synergize with ATR inhibitors to kill cancer cells.

bioRxiv · Jun 4, 2019Cancer Biology