Author

B. Tu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

C. Zhu· 2 shared H. Ying· 2 shared J. Yao· 2 shared L. Yan· 2 shared Q. Wang· 2 shared W. Yao· 2 shared Y. Kang· 2 shared A. Carugo· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCancer Biology

C. Zhu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Low-cost camera-based estrous tracking enables transgenesis in Peromyscus leucopus, the primary reservoir for Lyme disease

J. Buchthal, E. J. Chory, Z. Hill, C. Dennison, B. Tu, R. P. Wierenga, C. Cevrim, S. Golas, S. R. Telford, K. L. McKinley, R. Jaenisch, S. Markoulaki, K. M. Esvelt

bioRxiv · Oct 20, 2023 · PreprintBioengineering

Targeting glucose metabolism sensitizes pancreatic cancer to MEK inhibition

L. Yan, B. Tu, J. Yao, J. Gong, A. Carugo, C. Bristow, Q. Wang, C. Zhu, B. Dai, Y. Kang, L. Han, N. Feng, Y. Jin, J. Fleming, T. Heffernan, , H. Ying

This study shows that combining glucose metabolism inhibition with MEK inhibition enhances apoptosis in pancreatic cancer cells by inducing ER stress.

bioRxiv · Jan 9, 2021Cancer Biology

The Lon protease links nucleotide metabolism with proteotoxic stress

R. D. Zeinert, H. Baniasadi, B. Tu, P. Chien

This study shows that the Lon protease in Caulobacter crescentus regulates dNTP pools by degrading CcrM, linking nucleotide metabolism with proteotoxic stress response.

bioRxiv · Dec 10, 2019Microbiology

YAP1 Oncogene is a Context-specific Driver for Pancreatic Ductal Adenocarcinoma

B. Tu, J. Yao, S. Ferri-Borgogno, J. Zhao, S. Chen, Q. Wang, L. Yan, X. Zhou, C. Zhu, S. Bang, Q. Chang, C. A. Bristow, Y. Kang, H. Zheng, H. Wang, , H. Ying

This study identifies YAP1 as a context-specific driver for the squamous subtype of pancreatic ductal adenocarcinoma and shows WNT5A promotes tumor progression through YAP1 activation.

bioRxiv · Aug 17, 2019Cancer Biology

The Biological Evaluation of Fusidic Acid and Its Hydrogenation Derivative as Antimicrobial and Anti-inflammatory Agents

P. Wu, H. He, W. D. Hong, T. Wu, S. Zhao, X. Cui, Y. Zhong, D. Li, X. Xu, Z. Sheng, B. Tu, M. Gao, J. Zhou, S. Ward, P. M. O'Neill, K. Zhang

This study evaluates fusidic acid and its hydrogenation derivative for antimicrobial and anti-inflammatory effects against Gram-positive bacteria and in a mouse model.

bioRxiv · May 1, 2018Pharmacology & Toxicology