Combinatory differentiation of human induced pluripotent stem cells generates thymic epithelium that supports thymic crosstalk and directs dendritic- and CD4/CD8 T-cell full development
N. Provin, M. d'Arco, E. Kervagoret, A. Bruneau, L. Brusselle, C. Fourgeux, J. Poschmann, X. Saulquin, C. Guillonneau, L. David, M. Giraud
This study generates functional thymic epithelial cells from iPSCs that support T cell development and dendritic cell differentiation in vitro.
bioRxiv · Dec 23, 2023Immunology