L. Gil

The immune profile of circulating autoreactive CD4 T cells is imprinted through tissue activation during autoimmune liver diseases

This study identifies the transcriptional profile of circulating autoreactive CD4 T cells in autoimmune liver diseases and shows their functional relationship to liver-specific pathogenic clones.

Functional plasticity and recurrent cell states of malignant B cells in follicular lymphoma

This study identifies recurrent malignant B cell states in follicular lymphoma using single-cell RNA-seq and shows their functional plasticity and niche-specific localization.

No priming, just fighting - endophytic yeast attenuates the defense response and the stress induced by Dutch elm disease in Ulmus minor

This study investigates how an endophytic yeast reduces the defense response and stress in elm trees infected with Dutch elm disease.

A novel mouse model based on intersectional genetics enables unambiguous in vivo discrimination between plasmacytoid and other dendritic cells and their comparative characterization

This paper develops a pDC-reporter mouse model to unambiguously identify and compare pDC, pDC-like cells, and tDC in vivo, revealing distinct activation patterns during viral infection.

Viral infection engenders bona fide and bystander lung memory B cell subsets through permissive selection

The paper identifies two distinct lung memory B cell subsets post-viral infection, showing they arise from different progenitors and are classified as virus-specific or bystander based on antigen specificity.

Integrative molecular profiling of autoreactive CD4 T cells in autoimmune hepatitis

The paper characterizes autoreactive CD4 T cells in autoimmune hepatitis patients, identifying a specific phenotype linked to disease activity and IgG response.

Structure of core fungal endobiome in Ulmus minor: patterns within the tree and across genotypes differing in tolerance to Dutch elm disease

The paper identifies a core fungal endobiome in Ulmus minor trees, showing its presence across genotypes and health statuses, with some taxa linked to Dutch elm disease tolerance.

Endophyte inoculation enhances Ulmus minor resistance to Dutch elm disease

This study identifies an endophyte that reduces Dutch elm disease symptoms in Ulmus minor by inhibiting pathogen growth and inducing defense-related metabolites.

FB5P-seq: FACS-based 5-prime end single-cell RNAseq for integrative analysis of transcriptome and antigen receptor repertoire in B and T cells