The somatically generated T cell receptor CDR3a contributes to the MHC allele specificity of the T cell receptor
P. Marrack, S. H. Krovi, D. Silberman, J. White, E. Kushnir, M. Nakayama, J. Crook, T. Danhorn, S. Leach, R. Anselment, J. Scott-Browne, L. Gapin, J. Kappler
The paper shows that the somatically generated CDR3a of T cell receptors influences MHC allele specificity during positive selection.
bioRxiv · Aug 15, 2017Immunology