MicrobiologybioRxivPreprint
Biological and structural analysis of new potent Integrase-LEDGF allosteric HIV-1 inhibitors
E. Le Rouzic, D. Bonnard, F. Le Strat…·R. Benarous
This paper describes a new class of HIV-1 integrase-LEDGF allosteric inhibitors with potent anti-HIV activity, resistance to existing drugs, and a lead compound validated in a phase I trial.
DOI 10.1101/2023.01.28.523533