Author

E. Lippmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

A. Sorets· 2 shared B. O'Grady· 2 shared C. Duvall· 2 shared E. Hoogenboezem· 2 shared H. Kim· 2 shared A. Abdulrahman· 1 shared A. Bosworth· 1 shared A. Kjar· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioengineering

A. Sorets

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system

A. Sorets, K. Schwensen, N. Francini, A. Kjar, A. Abdulrahman, A. Shostak, K. Katdare, K. Schoch, R. Cowell, J. Park, A. Ligocki, W. Ford, L. Ventura-Antunes, E. Hoogenboezem, A. Prusky, , E. Lippmann

This study develops a lipid-siRNA conjugate that uses perivascular transport to achieve long-lasting gene knockdown in the CNS without toxicity.

bioRxiv · Jun 9, 2024 · PreprintBioengineering

Rapid Prototyping of Cell Culture Microdevices Using Parylene-Coated 3D Prints

B. O'Grady, M. Geuy, H. Kim, K. Balotin, E. Allchin, D. Florian, N. Bute, T. Scott, G. Lowen, C. Fricker, S. Guelcher, J. Wikswo, L. Bellan, E. Lippmann

This paper demonstrates that parylene coating makes 3D printed microdevices biocompatible and suitable for elastomeric device fabrication, enabling long-term cell viability and diverse device casting.

bioRxiv · Aug 2, 2021Bioengineering

Albumin-binding Aptamer Chimeras for Improved siRNA Bioavailability

J. Rosch, E. Hoogenboezem, A. Sorets, C. Duvall, E. Lippmann

This study develops albumin-binding aptamer-siRNA chimeras to enhance siRNA bioavailability, showing improved stability, gene knockdown, and extended circulation in vivo.

bioRxiv · Apr 15, 2021Bioengineering

Influence of substrate stiffness on barrier function in an iPSC-derived in vitro blood-brain barrier model

A. Bosworth, H. Kim, K. O'Grady, I. Richter, L. Lee, B. O'Grady, E. Lippmann

This study examines how substrate stiffness affects barrier function in iPSC-derived BBB endothelial-like cells, finding enhanced TEER on compliant substrates and no effect on P-glycoprotein activity.

bioRxiv · Mar 31, 2021Bioengineering

CRISPR-mediated isogenic cell-SELEX approach for generating highly specific aptamers against native membrane proteins

J. C. Rosch, E. H. Neal, D. A. Balikov, M. Rahim, E. Lippmann

The paper develops a CRISPR-mediated cell-SELEX method to generate specific aptamers against native membrane proteins by using isogenic cell lines for selection.

bioRxiv · Feb 17, 2020Bioengineering