Author

C. Duvall

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

E. Hoogenboezem· 2 shared J. Rosch· 2 shared A. Cavnar· 1 shared A. I. Borrachero-Conejo· 1 shared A. K. Locke· 1 shared A. Mahadevan-Jansen· 1 shared A. Sorets· 1 shared B. R. Dollinger· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioengineering

E. Hoogenboezem

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structural Optimization of siRNA Conjugates for Albumin Binding Achieves Effective MCL1-Targeted Cancer Therapy

E. Hoogenboezem, S. S. Patel, A. Cavnar, J. Lo, L. Babb, N. Francini, P. Patil, J. Colazo, D. L. Michell, V. Sanchez, J. McCune, J. Ma, C. DeJulius, L. Lee, J. Rosch, , C. Duvall

This paper optimizes siRNA conjugates for albumin binding to enhance tumor delivery and efficacy in cancer therapy, achieving 80% MCL1 silencing and improved survival in breast cancer models.

bioRxiv · Feb 14, 2023 · PreprintBioengineering

Nanoparticle-mediated transgene expression of insulin-like growth factor 1 in the growth restricted guinea pig placenta increases placenta nutrient transporter expression and fetal glucose concentrations

R. Wilson, K. Lampe, M. Gupta, C. Duvall, H. Jones

This study uses nanoparticle-mediated hIGF-1 gene therapy in a guinea pig model of FGR to increase placental nutrient transporter expression and fetal glucose concentrations.

bioRxiv · Jun 24, 2021Physiology

Visualizing the Role of Lipid Dynamics during Infrared Neural Stimulation with Hyperspectral Stimulated Raman Scattering Microscopy

W. R. Adams, R. Gautam, A. K. Locke, A. I. Borrachero-Conejo, B. R. Dollinger, G. A. Throckmorton, C. Duvall, E. D. Jansen, A. Mahadevan-Jansen

This study uses hyperspectral stimulated Raman scattering microscopy to observe lipid membrane dynamics during infrared neural stimulation in live neural cells, supporting the hypothesis that lipid packing order changes drive cell stimulation.

bioRxiv · May 24, 2021 · PreprintBiophysics

Albumin-binding Aptamer Chimeras for Improved siRNA Bioavailability

J. Rosch, E. Hoogenboezem, A. Sorets, C. Duvall, E. Lippmann

This study develops albumin-binding aptamer-siRNA chimeras to enhance siRNA bioavailability, showing improved stability, gene knockdown, and extended circulation in vivo.

bioRxiv · Apr 15, 2021Bioengineering