Author

E. Louka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:clustering· 1 Assay:multiome· 1

Frequent Co-Authors

A. Hamblin· 2 shared N. Sousos· 2 shared A. J. Mead· 1 shared A. L. Chedeville· 1 shared A. Mead· 1 shared A. Paterson· 1 shared A. Rao· 1 shared A. Rodriguez Meira· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

A. Hamblin

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2 papers

Recent·Most cited

Deciphering TP53 mutant Cancer Evolution with Single-Cell Multi-Omics

A. Rodriguez-Meira, R. Norfo, W. X. Wen, A. L. Chedeville, H. Rahman, J. OSullivan, G. Wang, E. Louka, W. Kretzschmar, A. Paterson, C. Brierley, J.-E. Martin, C. Demeule, M. Bashton, N. Sousos, , A. J. Mead

The paper uses single-cell multi-omic analysis to study TP53-mutant cancer evolution in leukaemia, identifying a role for chronic inflammation in promoting TP53 mutant clones.

bioRxiv · Mar 28, 2022 · PreprintCancer Biology

Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia

E. Louka, B. Povinelli, A. Rodriguez Meira, G. Buck, N. Ashley, A. Hamblin, C. A. G. Booth, N. Sousos, A. Roy, N. Elliott, D. Iskander, J. De la Fuente, N. Fordham, S. O'Byrne, S. Inglott, , A. Mead

This study identifies heterogeneous leukemia stem cells in JMML using single-cell RNA-sequencing and clonogenic assays, revealing their molecular features and potential therapeutic targets.

bioRxiv · May 7, 2019Cancer Biology