Author

E. M. Lofthouse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

J. K. Cleal· 2 shared A. Manousopoulou· 1 shared A. Page· 1 shared B. Ashley· 1 shared B. G. Sengers· 1 shared C. Cooper· 1 shared C. H. White· 1 shared C. Jenkinson· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPhysiology

J. K. Cleal

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2 papers

Recent·Most cited

Placental uptake and metabolism of 25(OH)Vitamin D determines its activity within the fetoplacental unit

B. Ashley, C. Simner, A. Manousopoulou, C. Jenkinson, F. Hey, J. M. Frost, F. I. Rezwan, C. H. White, E. M. Lofthouse, E. Hyde, L. Cooke, S. Barton, P. Mahon, E. M. Curtis, R. J. Moon, , J. K. Cleal

This study shows the human placenta actively transports and metabolizes 25(OH)D3 into active vitamin D metabolites, influencing fetal development through placental transcriptome and proteome changes.

eLife · Mar 8, 2022Peer-reviewedPhysiology

3D Visualisation of trans-syncytial nanopores provides a pathway for paracellular diffusion across the human placental syncytiotrophoblast

R. Lewis, H. Baskaran, J. Green, S. Tashev, E. Palaiologou, E. M. Lofthouse, J. K. Cleal, A. Page, D. Chatelet, P. Goggin, B. G. Sengers

The paper identifies trans-syncytial nanopores in the placental syncytiotrophoblast as pathways for paracellular diffusion, supported by 3D visualization and mathematical modeling.

bioRxiv · Jan 26, 2022Physiology