ImmunologybioRxiv
Plasmacytoid dendritic cells are functionally exhausted while non-haematopoietic sources of type I interferon dominate human autoimmunity
A. Psarras, A. Alase, A. Antanaviciute…·E. M. Vital
The paper shows that plasmacytoid dendritic cells are functionally exhausted in autoimmunity, and non-haematopoietic sources like keratinocytes drive type I interferon production.
DOI 10.1038/s41467-020-19918-z