Antibody targeting of aging damaged isoDGR-protein doubles lifespan in a mouse model of chronic inflammation
P. Kalailingam, K.-H. Mohd-Kahliab, S. C. Ngan, R. Iyappan, E. Melekh, T. Lu, G. W. Zien, B. Sharma, T. Guo, A. J. MacNeil, R. E. K. Macpherson, E. L. Tsiani, D. D. O'Leary, K. L. Lim, I. H. Su, , S. K. Sze
This paper shows that targeting aging-damaged isoDGR-proteins with antibodies extends lifespan in a mouse model of chronic inflammation.
bioRxiv · Mar 11, 2023 · PreprintBiochemistry