GRK2/3/5/6 knockout: The impact of individual GRKs on arrestin-binding and GPCR regulation
J. Drube, R. S. Haider, E. S. F. Matthees, M. Reichel, J. Zeiner, S. Fritzwanker, C. Ziegler, S. Barz, L. Klement, A. Kliewer, E. Miess, E. Kostenis, S. Schulz, C. Hoffmann
This study investigates the role of individual GRKs in GPCR regulation and β-arrestin interactions using GRK knockout cells and identifies distinct GRK-mediated mechanisms.
bioRxiv · Feb 12, 2021Cell Biology