E. Moller

On the lipid dependence of bacterial mechanosensitive channel gating in situ

This study investigates how different lipid species affect the function of mechanosensitive channels in E. coli, finding that cardiolipin is important for MscS adaptive behavior.

The lipid-mediated mechanism of mechanosensitive channel MscS inactivation

This study identifies a lipid-mediated mechanism by which the mechanosensitive channel MscS inactivates, showing that intercalated lipids physically decouple tension-sensing helices from the gate.

The dynamic hypoosmotic response of Vibrio cholerae relies on the mechanosensitive channel MscS

This study investigates the role of MscS and MscL channels in Vibrio cholerae's hypoosmotic response, showing MscS is critical for osmolyte release and survival.

MscS inactivation and recovery are slow voltage-dependent processes sensitive to interactions with lipids

This study investigates the voltage-dependent inactivation and recovery of MscS channels, showing that lipid-protein interactions significantly influence these processes.

Mechanosensitive channel MscS is critical for termination of the bacterial hypoosmotic permeability response

The paper shows that MscS is critical for terminating the bacterial hypoosmotic permeability response by inactivating MscL, ensuring proper membrane tension regulation.