Pharmacology & ToxicologybioRxiv
A standardised framework to identify optimal animal models for efficacy assessment in drug development
G. S. Ferreira, D. Veening-Griffioen, W. Boon…·P. van Meer
This paper develops a framework to assess and compare animal models for drug efficacy, showing that GRMD dogs better mimic Duchenne Muscular Dystrophy than mdx mice.