MicrobiologybioRxiv
Selection of HIV-1 for Resistance to Fifth Generation Protease Inhibitors Reveals Two Independent Pathways to High-Level Resistance
E. Spielvogel, S.-K. Lee, S. Zhou…·R. Swanstrom
This study identifies two independent resistance pathways to fifth-generation protease inhibitors in HIV-1 by analyzing mutations under high drug concentrations.
DOI 10.7554/elife.80328