Author

E. Oki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Assay:DNA methylation· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H. Kitao· 2 shared H. Saeki· 2 shared M. Iimori· 2 shared T. Wakasa· 2 shared Y. Kataoka· 2 shared Y. Maehara· 2 shared A. Harada· 1 shared A. K. Bharti· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

H. Kitao

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The anti-tumor effect of trifluridine via induction of aberrant mitosis is unaffected by mutations modulating p53 activity

T. Wakasa, M. Iimori, K. Nonaka, A. Harada, Y. Ohkawa, C. Kikutake, M. Suyama, T. Kobunai, K. Matsuoka, K. Tsunekuni, Y. Kataoka, H. Ochiiwa, K. Miyadera, T. Sagara, E. Oki, , H. Kitao

This study shows that trifluridine induces aberrant mitosis and cytotoxicity in both p53-null and p53-GOF mutant cells, independent of p53 function.

bioRxiv · Aug 30, 2023Cell Biology

CTDSP1 inhibitor rabeprazole regulates DNA-PKcs dependent topoisomerase I degradation and irinotecan drug resistance in colorectal cancer

H. Matsuoka, K. Ando, E. J. Swayze, E. C. Unan, J. Mathew, Q. Hu, Y. Tsuda, Y. Nakashima, H. Saeki, E. Oki, A. K. Bharti, M. Mori

This study shows that rabeprazole inhibits CTDSP1, which promotes irinotecan resistance in colorectal cancer by enhancing DNA-PKcs-mediated topoisomerase I degradation.

bioRxiv · Jan 7, 2020Cancer Biology

DNA replication stress induced by trifluridine determines tumor cell fate according to p53 status

Y. Kataoka, M. Iimori, R. Fujisawa, T. Morikawa-Ichinose, S. Niimi, T. Wakasa, H. Saeki, E. Oki, D. Miura, T. Tsurimoto, Y. Maehara, H. Kitao

This paper shows that trifluridine induces DNA replication stress that leads to different cell fates in tumor cells depending on their p53 status.

bioRxiv · Sep 13, 2019Cancer Biology