MUC13 negatively regulates tight junction proteins and intestinal epithelial barrier integrity via Protein Kinase C
C. Segui-Perez, D. Stapels, Z. Ma, J. Su, E. Passchier, B. Westendorp, W. Wu, J. P. van Putten, K. Strijbis
This study shows MUC13 regulates tight junction proteins and intestinal barrier integrity through Protein Kinase C, with deletion of MUC13 increasing TJ protein levels and altering barrier function.
bioRxiv · Oct 27, 2022Cell Biology