Author

E. Pick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Sinha· 2 shared A. Thakur· 1 shared B. E. Lemma· 1 shared D. Fushman· 1 shared D. Harshuk-Shabso· 1 shared D. Kornitzer· 1 shared E. Berda· 1 shared G. Dittmar· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

A. Sinha

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Redox-driven control of Yuh1/UCHL3 impacts mitochondrial health via NEDD8/Rub1 pathway

S. Issa, Y. Klein, E. Berda, D. Harshuk-Shabso, A. Sinha, Y. Sharaby, M. Benhar, E. Pick

The paper investigates how redox changes affect Yuh1/UCHL3 activity, revealing a thiol-based redox switch that modulates NEDD8/Rub1 processing and impacts mitochondrial health.

bioRxiv · May 20, 2024 · PreprintCell Biology

Rub1/NEDD8, a ubiquitin-like modifier, is also a ubiquitin modifier

S. Zerath Gurevich, A. Sinha, J. Longworth, R. K. Singh, B. E. Lemma, A. Thakur, O. Popp, D. Kornitzer, N. Reis, M. Scheffner, G. Dittmar, E. Pick, D. Fushman, M. H. Glickman

This paper shows that a single amino acid swap at position 72 can switch the substrate specificity of Rub1/NEDD8 and ubiquitin, revealing their distinct roles in cellular modification pathways.

bioRxiv · Jun 18, 2020 · PreprintBiochemistry