B. Wagner

SARS-CoV-2 serosurvey of healthy, privately owned cats presenting to a New York City animal hospital in the early phase of the COVID-19 pandemic (2020-2021)

This study reports a serosurvey of cats in New York City during the early pandemic, finding 16% seropositive for SARS-CoV-2 with higher prevalence in fall 2020 and evidence of human-cat transmission.

Modeling cellular self-organization in strain-stiffening hydrogels

The paper develops a 3D mathematical model to study cell population dynamics in strain-stiffening hydrogels, showing chain formation and nonlinear mechanical responses under stretching and solvent exchange.

Top dressed biochar increases tree seedling growth and decreases sodium leaching

This study tests if biochar reduces sodium leaching and improves tree growth under salt stress, finding top-dressed biochar decreases leaching and benefits seedling growth.

FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity

FALCON systematically analyzes 61 free fatty acids to identify lipotoxic effects and a novel mediator of lipotoxicity, CMIP, in human pancreatic beta cells.

Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses

This study develops a method to purify human α-cells with >97% purity using a fluorescent probe, enabling functional and transcriptomic analyses.

Predicting disordered regions driving phase separationof proteins under variable salt concentration

The paper predicts disordered regions driving phase separation of proteins under variable salt concentration using a theoretical model validated against experimental data.

A linear SARS-CoV-2 DNA vaccine candidate reduces virus shedding in ferrets

This study evaluates a linear SARS-CoV-2 DNA vaccine delivered via electroporation in ferrets, showing reduced virus shedding and immune responses.

Conjunctival epithelial cells resist productive SARS-CoV-2 infection

The paper investigates whether conjunctival epithelial cells can be infected by SARS-CoV-2 and finds that while genome expression occurs, productive infection does not.

A single-cell atlas of lymphocyte adaptive immune repertoires and transcriptomes reveals age-related differences in convalescent COVID-19 patients

This study uses single-cell sequencing to analyze immune repertoires and transcriptomes in convalescent COVID-19 patients, revealing age-related differences in T and B cell responses.

Single-cell sequencing of plasma cells from COVID-19 patients reveals highly expanded clonal lineages produce specific and neutralizing antibodies to SARS-CoV-2

Single-cell sequencing and screening identify expanded plasma cell clones in COVID-19 patients producing SARS-CoV-2-specific neutralizing antibodies.

Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2

This study shows white-tailed deer are susceptible to SARS-CoV-2 infection, shedding virus in nasal secretions and transmitting it to contact animals.

Myosin 10 and a Cytoneme-Localized Ligand Complex Promote Morphogen Transport

The paper shows Myosin 10 and BOC/CDON co-receptor facilitate SHH morphogen transport via cytonemes.

BrainNET: Inference of brain network topology using Machine Learning

BrainNET, a machine learning method for fMRI network inference, outperforms correlation and partial correlation in identifying brain network changes in ADHD.

The expression of equine keratins K42 and K124 is restricted to the hoof epidermal lamellae of Equus caballus

The paper identifies K42 and K124 as lamellar-specific keratins in equine hooves and validates monoclonal antibodies against them.

6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion

This study identifies 6-phosphogluconate dehydrogenase (PGD) as essential for ER structural integrity and protein secretion, linking cytosolic carbohydrate metabolism to ECM secretion processes.