Direct anabolic three carbon metabolism via propionate to a six carbon metabolite occurs in human heart and in vivo across mouse tissues
M. T. Doan, M. D. Neinast, E. L. Varner, K. Bedi, D. Bartee, H. Jiang, S. Trefely, P. Xu, J. P. Singh, C. Jiang, E. Rame, D. Brady, J. L. Meier, K. Marguiles, Z. Arany, N. W. Snyder
The paper confirms the in vivo synthesis of a six-carbon metabolite from propionate in human heart and mouse tissues through non-oxidative pathways.
bioRxiv · Jun 15, 2020 · PreprintBiochemistry