NG2+/Nestin+ mesenchymal stem cells dictate DTC dormancy in the bone marrow through TGFβ2
A. R. Nobre, E. Risson, D. K. Singh, J. S. Di Martino, J. F. Cheung, J. Wang, J. Johnson, H. G. Russnes, J. J. Bravo-Cordero, A. Birbrair, B. Naume, M. Azhar, P. S. Frenette, J. A. Aguirre-Ghiso
This study shows NG2+/Nestin+ mesenchymal stem cells in the bone marrow use TGFβ2 to induce dormancy in breast cancer disseminated tumor cells.
bioRxiv · Oct 22, 2020Cancer Biology