M. Azhar

HEMATO-CHEMICAL VARIATIONS- A DIAGNOSTIC TOOL FOR BABESIA, THEILERIA AND ANAPLASMA INFECTIONS IN CAPTIVE HOG DEER (AXIS PORCINUS)

This study identifies hemato-chemical parameter changes in hog deer infected with Theileria, Babesia, and Anaplasma to develop diagnostic tools for early detection of these parasites.

Momelotinib is a highly potent inhibitor of FLT3-mutant AML

This study shows momelotinib is a potent FLT3 inhibitor effective against FLT3-mutant AML, including resistant variants, and suppresses resistance mechanisms like FLT3 ligand and cytokine signaling.

Effects of Emodin, a Plant-Derived Anthraquinone, on TGFβ1-Induced Cardiac Fibroblast Activation and Function

This study shows emodin reduces TGFβ1-induced cardiac fibroblast activation and collagen accumulation by modulating key signaling pathways.

Mutagenesis Mapping of RNA Structures within the Foot-and-Mouth Disease Virus Genome Reveals Functional Elements Localised in the Polymerase (3Dpol) Encoding Region.

The paper identifies three critical RNA structures in the FMDV genome essential for replicon replication, while 42 others are non-essential, suggesting potential targets for vaccine development.

NG2+/Nestin+ mesenchymal stem cells dictate DTC dormancy in the bone marrow through TGFβ2

This study shows NG2+/Nestin+ mesenchymal stem cells in the bone marrow use TGFβ2 to induce dormancy in breast cancer disseminated tumor cells.

A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

This study develops a vaccine candidate using SpyCatcher technology to display the SARS-CoV-2 RBD, showing strong neutralizing antibody responses in mice and pigs.

TUTase mediated site-directed access to clickable chromatin employing CRISPR-dCas9

This paper develops sgRNA-Click (sgR-CLK), a method to site-directly display synthetic molecules on chromatin using CRISPR-dCas9 and bioorthogonal click chemistry.