Unlocking cellular plasticity: Enhancing human iPSC reprogramming through bromodomain inhibition and extracellular matrix gene expression regulation
T. K. Archer, J. Yang, H. K. Kinyamu, J. Ward, E. Scappini
This study shows that PFI-3 enhances iPSC reprogramming by promoting mesenchymal-epithelial transition and reducing extracellular matrix gene expression in human fibroblasts.
bioRxiv · Oct 13, 2023Cell Biology