E. SEVERI

Characterisation of anhydro-sialic acid transporters from mucosa-associated bacteria

The paper identifies and characterizes anhydro-sialic acid transporters in bacteria, showing their specific or promiscuous substrate preferences.

Identification of novel tail-anchored membrane proteins integrated by the bacterial twin-arginine translocase

The paper identifies novel tail-anchored Tat substrates in bacterial genomes through bioinformatics and experimental validation, revealing new iron-sulphur proteins and candidate substrates without cofactors.

Characterisation of a TatA/TatB binding site on the TatC component of the Escherichia coli twin arginine translocase

This study investigates the role of a second TatA binding site on TatC in Escherichia coli by mutagenesis and shows that while TatA binding is reduced, TatC retains function.

The structure of HiSiaQM defines the architecture of tripartite ATP-independent periplasmic (TRAP) transporters

This paper presents the first cryo-EM structure of TRAP transporter membrane domains and identifies structural features that enable monomeric elevator architecture.

Multiple evolutionary origins reflect the importance of sialic acid transporters in the colonisation potential of bacterial pathogens and commensals.

This study identifies multiple evolutionary origins of sialic acid transporters in bacteria, highlighting their role in host-microbe interactions and microbial colonization.