Sexual identity of enterocytes regulates rapamycin-mediated intestinal homeostasis and lifespan extension
J. C. Regan, Y.-X. Lu, E. Urena, R. Meilenbrock, J. H. Catterson, D. Kissler, L. Partridge
This study shows that rapamycin extends lifespan in female Drosophila but not males, due to sex-specific autophagy regulation in intestinal enterocytes.
bioRxiv · Oct 22, 2021 · PreprintPhysiology