BiophysicsbioRxiv
The Kinesin-5 Tail Domain Directly Modulates the Mechanochemical Cycle of the Motor for Anti-Parallel Microtubule Sliding
T. Bodrug, E. Wilson-Kubalek, S. Nithianantham…·J. Al-Bassam
This study shows the kinesin-5 tail domain regulates motor activity by modulating ATP hydrolysis and microtubule sliding, leading to slow motility and force generation.
DOI 10.7554/elife.51131