BiophysicsbioRxivPreprint
PDZ Domains from the Junctional Proteins Afadin and ZO-1 Act as Mechanosensors
Vipul T. Vachharajani, Matthew P. DeJong, Soumya Dutta…·Alexander R. Dunn
This study shows that PDZ domains from afadin and ZO-1 act as mechanosensors, forming catch bonds or weakening under mechanical force, affecting cell-cell adhesion stability.