NeuroscienceScientific ReportsPeer-reviewed
Physiological significance of proteolytic processing of Reelin revealed by cleavage-resistant Reelin knock-in mice
Eisuke Okugawa, Himari Ogino, Tomofumi Shigenobu…·Mitsuharu Hattori
This study shows that inhibiting Reelin cleavage enhances its signaling, leading to hippocampal layer disturbances and increased dendritic branching, suggesting Reelin cleavage is critical for normal brain development.
29 citations