Cancer BiologybioRxivPreprint
Metabolic Salvage and Acyl-chain Remodeling Support Glycosphingolipid Synthesis within the PDAC Tumor Microenvironment
Anna Trimble, Casie S. Kubota, Elaine Zhao…·Christian M. Metallo
The paper uses 13C metabolic flux analysis on PDAC tumor slice cultures to identify metabolic pathways supporting glycosphingolipid synthesis and highlight the role of PIKfyve in lipid homeostasis.