Cell BiologybioRxivPreprint
CRISPR/Cas9-mediated Generation of COL7A1-deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa
Farzad Alipour, Mana Ahmadraji, Elham Yektadoost…·Mohsen Basiri
The paper generates COL7A1-deficient keratinocyte cell lines using CRISPR/Cas9 to model RDEB and shows reduced type VII collagen expression and increased cell motility.
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