Cell BiologyCell ReportsPeer-reviewed
Proteomic Analysis Reveals a PLK1-Dependent G2/M Degradation Program and Links PKA-AKAP2 to Cell Cycle Control
Ryan D. Mouery, Kimberly Lukasik, Carolyn Hsu…·Michael J. Emanuele
The paper uses proteomics and PLK1 inhibition to identify proteins degraded at G2/M, showing PLK1's role in coordinating proteolysis via SCF ligases and linking AKAP2 to cell cycle control.
18 citations