Author

Emanuel Jeldes

Cancer Research UK Scotland Institute

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

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Björn KruspigiD· 1 shared Colin S. WoodiD· 1 shared Daniel L. Murphy· 1 shared David P. SumptoniD· 1 shared Douglas StrathdeeiD· 1 shared Holly LeslieiD· 1 shared Ian R. PowleyiD· 1 shared Jim C. NormaniD· 1 shared

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1 shared paperCancer Biology

Björn KruspigORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMar 19, 2025

Increased mRNA translation delays lung adenocarcinoma initiation and exposes a therapeutic vulnerability to MEK inhibitors

Luis Pardo, Madeleine Moore, Ruhi S. Deshmukh…·Jim C. Norman

This study shows that increased mRNA translation delays lung adenocarcinoma initiation and creates a vulnerability to MEK inhibitors in KRAS-driven tumors.

DOI 10.1101/2025.03.19.644135

mousebulk RNA-seq

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