Author

Björn Kruspig

Cancer Research UK Scotland InstituteORCID 0000-0002-1712-5411Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:flow cytometry· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

John P. C. Le QuesneiD· 2 shared Lynn McGarryiD· 2 shared Amanda J. McFarlane· 1 shared Calum C. BainiD· 1 shared Colin NixoniD· 1 shared Colin S. WoodiD· 1 shared Crispin J. MilleriD· 1 shared Daniel J. MurphyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

John P. C. Le QuesneORCID

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2 papers

Recent·Most cited

ImmunologyScience AdvancesPeer-reviewedMar 4, 2026

γδ T cells impair airway macrophage differentiation in lung adenocarcinoma

Ximena L. Raffo Iraolagoitia, Amanda J. McFarlane, Sarah Laing…·Leo M. Carlin

The paper identifies that CD27+ γδ T cells impair the differentiation of tumor-associated macrophages into airway macrophages in lung adenocarcinoma.

1 citation

mouseflow cytometry

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Cancer BiologybioRxivPreprintMar 19, 2025

Increased mRNA translation delays lung adenocarcinoma initiation and exposes a therapeutic vulnerability to MEK inhibitors

Luis Pardo, Madeleine Moore, Ruhi S. Deshmukh…·Jim C. Norman

This study shows that increased mRNA translation delays lung adenocarcinoma initiation and creates a vulnerability to MEK inhibitors in KRAS-driven tumors.

DOI 10.1101/2025.03.19.644135

mousebulk RNA-seq

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