Optimization and Characterization of SHIP1 Ligands for Cellular Target Engagement and Activity in Alzheimer's Disease Models
Cynthia D. Jesudason, Claudia Rangel‐Barajas, Colin J Beach…·Timothy I. Richardson
This study identifies SHIP1 ligands with brain exposure and in vivo activity in Alzheimer's models, showing target engagement and reduced neuroinflammation.