Cancer BiologyDevelopmental CellPeer-reviewed
FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma
Katherine Gillis, Walter A. Orellana, Emily Wilson…·Eric L. Snyder
This study shows FoxA1/2 reprogram the epigenome of NKX2-1-negative lung adenocarcinoma to drive a gastric lineage switch through DNA demethylation and regulatory element activation.
23 citations