Cancer BiologyCell ReportsPeer-reviewed
Acod1 Expression in Cancer Cells Promotes Immune Evasion through the Generation of Inhibitory Peptides
James H. Schofield, Joseph Longo, Ryan D. Sheldon…·Zachary T. Schafer
This study shows that Acod1 in cancer cells promotes immune evasion by releasing inhibitory peptides, not ITA, and that reducing Acod1 can make tumors responsive to PD-1 therapy.
18 citations