Author

Emmanuelle Braud

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Biochemistry· 1

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Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

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Amedeo CaflischiD· 1 shared Danzhi Huang· 1 shared Dylan Coelho· 1 shared Ivan CorbeskiiD· 1 shared Jiahua DengiD· 1 shared Laura Iannazzo· 1 shared Mélanie Ethève-QuelquejeuiD· 1 shared Pablo Andrés Vargas-RosalesiD· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperBiochemistry

Amedeo CaflischORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintSep 6, 2023

The catalytic mechanism of the RNA methyltransferase METTL3

Ivan Corbeski, Pablo Andrés Vargas-Rosales, Rajiv Kumar Bedi…·Amedeo Caflisch

This study reveals the catalytic mechanism of METTL3-14 by identifying two adenosine binding conformations, the methyl transfer transition state, and the roles of key residues in catalysis.

DOI 10.1101/2023.09.06.556513

humanstructural biology

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