Author

R.K. Bedi

Indian Institute of Technology BombayORCID 0000-0002-8193-9006Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Abhishek B. SuryawanshiiD· 1 shared Amedeo CaflischiD· 1 shared Danzhi Huang· 1 shared Dylan Coelho· 1 shared Emmanuelle Braud· 1 shared Ivan CorbeskiiD· 1 shared Jiahua DengiD· 1 shared Laura Iannazzo· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

Abhishek B. SuryawanshiORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJan 2, 2025

Rewiring Catalytic Craters: A Path for Engineering β-Glucosidases to Improve Glucose Tolerance

Abhishek B. Suryawanshi, R.K. Bedi, Meera Pawar…·Prasenjit Bhaumik

This paper engineers β-glucosidases to improve glucose tolerance by analyzing structural changes and mutations that enhance catalytic efficiency and stability.

1 citation

protein structureexperimental assay

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BiochemistrybioRxivPreprintSep 6, 2023

The catalytic mechanism of the RNA methyltransferase METTL3

Ivan Corbeski, Pablo Andrés Vargas-Rosales, Rajiv Kumar Bedi…·Amedeo Caflisch

This study reveals the catalytic mechanism of METTL3-14 by identifying two adenosine binding conformations, the methyl transfer transition state, and the roles of key residues in catalysis.

DOI 10.1101/2023.09.06.556513

humanstructural biology

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