BiophysicsNature CommunicationsPeer-reviewed
Structural and Dynamic Insights into the Biased Signaling Mechanism of the Human Kappa Opioid Receptor
Chiyo Suno-Ikeda, Ryo Nishikawa, Riko Suzuki…·Ryoji Suno
This study investigates the structural dynamics of the human KOR-Gi signaling complex with G-protein-biased and balanced agonists, identifying key residues involved in signaling bias.