Erik P. Myers

This study investigates how cyclical compression and shear deformations affect central metabolites in chondrocytes, showing changes in metabolites that could inform therapeutic mechanotransduction for cartilage repair.

This study develops a stoichiometric model of chondrocyte metabolism to examine how cyclical shear and compressive loading affect matrix protein synthesis, revealing sex-dependent differences and nitrogen limitations.

This study develops a 3D culture system for chondrocytes that supports pericellular matrix development and enables mechanotransduction studies through metabolomic profiling.

This study tests diffusion of 3kDa tracers from bone-to-cartilage in bovine osteochondral cores under different loading conditions and finds significant fluid transport with cyclic compression affecting tracer concentration.

The paper measures thermal properties of agarose hydrogels and compares them to articular cartilage, finding similar thermal characteristics.