GeneticsbioRxivPreprint
Age-dependent ribosomal DNA variations and their effect on cellular function in mammalian cells
Eriko Watada, Sihan Li, Yutaro Hori…·Takehiko Kobayashi
This study identifies age-dependent changes in rDNA copy number, methylation, and sequence variations in mice, linking these alterations to reduced pre-rRNA levels and shortened yeast lifespan.
2 citations