Author

F. A. Dick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

M. Roes· 2 shared S. J. Kim· 2 shared A. Chaikovsky· 1 shared A. Marshall· 1 shared C. Howlett· 1 shared D. T. Passos· 1 shared J. I. MacDonald· 1 shared J. Sage· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

M. Roes

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A genome wide CRISPR screen reveals that HOXA9 promotes enzalutamide resistance in prostate cancer

F. A. Dick, M. Roes

A CRISPR screen identifies HOXA9 as a driver of enzalutamide resistance in prostate cancer, with its inhibition showing synergy with enzalutamide.

bioRxiv · Dec 15, 2023Cancer Biology

EZH2 inhibition stimulates viral mimicry in resting splenic B cells

F. A. Dick, S. J. Kim, P. K. Kiser, R. P. DeKoter

EZH2 inhibition causes repeat misexpression and B cell death by mimicking viral infection in splenic B cells.

bioRxiv · May 8, 2023 · PreprintPathology

Phosphorylation of the RB C-terminus regulates condensin II release from chromatin

S. J. Kim, J. I. MacDonald, F. A. Dick

This study shows that phosphorylation of RB at S838/T841 regulates its interaction with condensin II on chromatin, affecting genome stability.

bioRxiv · Oct 22, 2020Cancer Biology

RB1 deletion in RB-pathway disrupted cells results in DNA damage and cancer progression.

A. Marshall, M. Roes, D. T. Passos, M. DeWeerd, A. Chaikovsky, J. Sage, C. Howlett, F. A. Dick

This study shows that RB1 mutations in already compromised RB-pathway cells increase DNA damage and cancer progression through genomic instability and impaired repair mechanisms.

bioRxiv · Mar 23, 2019Cancer Biology