EZH2 inhibition stimulates viral mimicry in resting splenic B cells
F. A. Dick, S. J. Kim, P. K. Kiser, R. P. DeKoter
EZH2 inhibition causes repeat misexpression and B cell death by mimicking viral infection in splenic B cells.
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F. A. Dick, S. J. Kim, P. K. Kiser, R. P. DeKoter
EZH2 inhibition causes repeat misexpression and B cell death by mimicking viral infection in splenic B cells.
H. L. Raczkowski, L. S. Xu, W. C. Wang, R. P. DeKoter
The paper investigates how external signals regulate Spi-C expression in B cells, showing that factors like lipopolysaccharide and cytokines reduce Spic levels, while some treatments partially prevent this downregulation.
J. Rhee, L. A. Solomon, R. P. DeKoter
This study shows that ATP Citrate Lyase (ACL) regulates cell cycle progression during myeloid differentiation by affecting acetyl-CoA availability for fatty acid synthesis and histone acetylation.