BiochemistrybioRxiv
Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli
S. Zheng, L.-T. Sham, F. A. Rubino…·A. C. Kruse
The paper reports the crystal structure of MurJ from E. coli, performs mutagenesis to map functional sites, and identifies co-evolved interactions supporting a rocker-switch model for lipid II transport.
DOI 10.1073/pnas.1802192115