MicrobiologybioRxiv
Cellular barcoding of protozoan pathogens reveals the within-host population dynamics of Toxoplasma gondii host colonization
C. J. Wincott, G. Sritharan, H. J. Benns…·M. A. Child
The paper develops a CRISPR-based barcoding method for protozoa and applies it to Toxoplasma gondii, showing the blood-brain barrier is not a major bottleneck for colonization.
DOI 10.1016/j.crmeth.2022.100274