E. Alves

Combining IP3 affinity chromatography and bioinformatics reveals a novel protein-IP3 binding site on Plasmodium falciparum MDR1 transporter

The paper identifies a potential IP3-binding site on the Plasmodium falciparum MDR1 transporter using IP3 affinity chromatography and bioinformatics.

An extracellular redox signal triggers calcium release and impacts the asexual development of Toxoplasma gondii

This study shows that extracellular redox signals trigger calcium release in Toxoplasma gondii, affecting its asexual development and egress.

Prioritization of antimicrobial targets by CRISPR-based oligo recombineering

This paper introduces CORe, a CRISPR-based method to prioritize reactive amino acids for drug discovery by linking sequence reactivity to protein function in Toxoplasma gondii.

Cellular barcoding of protozoan pathogens reveals the within-host population dynamics of Toxoplasma gondii host colonization

The paper develops a CRISPR-based barcoding method for protozoa and applies it to Toxoplasma gondii, showing the blood-brain barrier is not a major bottleneck for colonization.

Dissection-independent production of a protective whole-sporozoite malaria vaccine

A four-step process isolates pure malaria sporozoites from mosquitoes without manual dissection, enabling a whole-parasite vaccine that provides sterilizing protection.

Generation of a novel SARS-CoV-2 sub-genomic RNA due to the R203K/G204R variant in nucleocapsid: homologous recombination has potential to change SARS-CoV-2 at both protein and RNA level

The paper identifies a novel SARS-CoV-2 sub-genomic RNA generated by homologous recombination involving the R203K/G204R variant in nucleocapsid, which may enhance viral adaptation and expression.

Pyricularia graminis-tritici sp. nov., a new Pyricularia species causing wheat blast

The paper identifies a new Pyricularia species, Pyricularia graminis-tritici, causing wheat blast, through phylogenetic analysis of isolates from wheat and related grasses.