Structural principles of B-cell antigen receptor assembly
Y. Dong, X. Pi, F. Bartels-Burgahn, D. Saltukoglu, Z. Liang, J. Yang, Y. Zheng, F. W. Alt, M. Reth, H. Wu
This paper reports cryo-EM structures of the IgM BCR and its Fab-deleted form, revealing an asymmetric arrangement and novel structural principles of BCR assembly.
bioRxiv · Aug 13, 2022Immunology