The translational role of SOS1 in colorectal cancer
D. Alem, X. Yang, F. Beato, B. Sarcar, A. F. Tassielli, R. Dai, T. L. Hogenson, M. A. Park, K. Jiang, J. Cai, Y. Yuan, M. E. Fernandez-Zapico, A. C. Tan, J. B. Fleming, H. Xie
This paper investigates the role of SOS1 in colorectal cancer using patient-derived organoids and identifies SOS1 protein expression as a predictive marker for response to SOS1 inhibitors.
bioRxiv · Oct 14, 2022 · PreprintCancer Biology